meaning of smallpox
1. A contagious, constitutional, febrile disease characterized by a peculiar eruption; variola. The cutaneous eruption is at first a collection of papules which become vesicles (first flat, subsequently umbilicated) and then pustules, and finally thick crusts which slough after a certain time, often leaving a pit, or scar.
2. a highly contagious viral disease characterized by fever and weakness and skin eruption with pustules that form scabs that slough off leaving scars